1. (1)Ryota Saito, Moe Tamura,a Saya Kawano, Yutaka Yoshikawa, Akihiro Kato, Kaname Sasaki, and Hiroyuki Yasui “Synthesis and biological evaluation of 4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxamides and their zinc(II) complexes as candidate antidiabetic agents ” New J. Chem., 2017, 41, 5572–5581.

  2. (2)Ryota Saito, Maiko Hoshi, Akihiro Kato, Chikako Ishikawa, Toshiya Komatsu “Green fluorescent protein chromophore derivatives as a new class of aldose reductase inhibitors” Eur. J. Med. Chem. 2017, 125, 965–974.

  3. (3)Toru Hatanaka, Ryosuke Yuki, Ryota Saito, Kaname Sasaki “alpha-Methylphenacyl thioesters as convenient thioacid precursors” Org. Biomol. Chem., 2016,14, 10589–10592.

  4. (4)Yusuke Hashimoto, Saki Tanikawa, Ryota Saito, Kaname Sasaki “beta-Stereoselective mannosylation using 2,6-lactones” J. Am. Chem. Soc., 2016, 138, 14840–14843.

  5. (5)Ryota Saito, Saori Suzuki, and Kaname Sasaki “Pterin-7-carboxamides as a New Class of Aldose Reductase Inhibitors” Bioorg. Med. Chem. Lett. 2016, 26, 4870–4874.

  6. (6)Ryota Saito, Takashi Hirano, Shojiro Maki, and Haruki Niwa  “Synthesis and Chemiluminescent Properties of 6,8-Diaryl-2-methylimidazo[1,2-a]pyrazin-3(7H)-ones: Systematic Investigation of Substituent Effect at para-Position of Phenyl Group at 8-Position” J. Photochem. Photobiol., A, 2014, 293, 12-25.

  7. (7)Paul A. Wiget, Lawrence A. Manzano, Jeff M. Pruet, Grace Gao, Ryota Saito, Arthur F.  Monzingo, Karl R. Jasheway, Jon D. Robertus,* Eric V. Anslyn “Sulfur incorporation generally improves Ricin inhibition in pterin-appended glycine-phenylalanine dipeptide mimics” Bioorg. Med. Chem. Lett., 2013, 6799–6804.

  8. (8)Ryota Saito, Jeff M. Pruet, Lawrence A. Manzano, Karl Jasheway, Arthur F. Monzingo, Paul A. Wiget, Ishan Kamat, Eric V. Anslyn, and Jon D. Robertus “Peptide-Conjugated Pterins as Inhibitors of Ricin Toxin A” J. Med. Chem. 2013, 56, 320-329.

  9. (9)Jeff M. Pruet, Ryota Saito, Lawrence A. Manzano, Karl R. Jasheway, Paul A. Wiget, Ishan Kamat, Eric V. Anslyn, and Jon D. Robertus “Optimized 5-Membered Heterocycle-Linked Pterins for the Inhibition of Ricin Toxin A” ACS Med. Chem. Lett., 2012, 3, 588–591.

  10. (10)Hikaru Kawarada, Yutaka Yoshikawa, Hiroyuki Yasui, Shunsuke Kuwahara, Yoichi Habata, and Ryota Saito “Synthesis and In Vitro Insulin-Mimetic Activities of Zinc(II) Complexes of Ethyl 2,5-Dihydro-4-hydroxy-5-oxo-1H-pyrrole-3-carboxylates” Metallomics, 2011, 3 (7), 675-679.

  11. (11)Xing-Ri CUI, Ryota SAITO, Takatsugu KUBO, Daijiro KON, Yuich HIRANO, and Setsuo SAITO “Preparations of Anthraquinone and Naphthoquinone Derivatives and Their Cytotoxic Effects” Chem. Pharm. Bull., 2011, 59(3), 302–314.

  12. (12)Ryota Saito, Takashi Hirano, Shojiro Maki, Haruki Niwa, and Mamoru Ohashi “Influence of Electron-donating and Electron-withdrawing Substituents on the Chemiluminescence Behavior of Coelenterazine Analogs” Bull. Chem. Soc. Jpn., 2011, 84(1), 90–99.

  13. (13)Ryota Saito “Non-CRET-based Green Chemiluminescence of Imidazopyrazinone Modified by 2,3,6,7-tetrahydro-1H,5H-benzo[ij]quinolizine as a Strong Electron-donating Unit” Heterocycles, 2010, 81(12), 2831–2840.

  14. (14)Ryota Saito and Eri Ito “Synthesis of Readily Accessible BODIPY-based Fluorescence Derivatization Reagents for Amines” Heterocycles, 2010, 81(11), 2599–2608.

  15. (15)Ryota Saito, Yuriko Matsumura, Saori Suzuki, and Naoki Okazaki, “Intensely blue-fluorescent 2,5-bis(benzoimidazol-2-yl)pyrazine dyes with improved solubility: Their synthesis, fluorescent properties, and application as microenvironment polarity probes.” Tetrahedron, 2010, 66, 8273–8279.

  16. (16)Ryota Saito, Ayako Ohno, and Eri Ito “Synthesis of Boradiazaindacene-Imidazopyrazinone Conjugate as Lipophilic and Yellow-Chemiluminescent Chemosensor for Superoxide Radical Anion”, Tetrahedron, 2010, 66, 583–590.

  17. (17)R. Saito, M. Tokita, K. Uda, C. Ishikawa, M. Satoh "Synthesis and in vitro evaluation of botryllazine B analogues as a new class of inhibitor against human aldose reductase", Tetrahedron, 2009, 65(15), 3019–3026.

  18. (18)M. Fujii, S. Ishii, R. Saito, H. Akita “Enzymatic resolution of albicanol and its application to the synthesis of (-)-copalic acid”, J. Mol. Cat. B: Enzymatic, 2009, 59, 254–260.

  19. (19)M. Fujii, S. Ishii, R. Saito, H. Akita, “Determination of the Absolute Structure of Albaconol”, Tetrahedron, 2008, 5147–5149.

  20. (20)R. Saito, S. Machida, S. Suzuki, and A. Katoh, “Synthesis and Spectroscopic Properties of 2,5-Bis(benzoazol-2-yl)pyrazines”, Heterocycles, 2008, 75 (3), 531–536.

  21. (21)M. Sugaya, R. Saito, Y. Matsumura, K. Harada, and A. Katoh, “Facile detection of RNA-polypeptide interactions by MALDI-Tof mass spectrometry”, J. Pept. Sci., 2008, 14, 978–983.

  22. (22)M. Fujii, S. Ishii, R. Saito, H. Akita, “Determination of the Absolute Structure of Albaconol”, Tetrahedron, 2008, 5147–5149.

  23. (23)Y. Nishiyama, M. Kaneda, S. Asaoka, R. Saito, T. Mori, T. Wada, and Y. Inoue, “Mechanistic Study on the Enantiodifferentiating Anti-Markovnikov Photoaddition of Alcohols to 1,1-Diphenyl-1-alkenes in Near-Critical and Supercritical Carbon Dioxide”, J. Phys. Chem. A, 2007, 111 (51), 13432–13440.

  24. (24)M. Yamaguchi, R. Saito, Y. Adachi, Y. Yoshikawa, H. Sakurai, and A. Katoh, “Synthesis of Oxovanadium(IV) and Zinc(II) Complexes of 3-Hydroxy-4-(p-substituted)phenylthiazole-2(3H)-thiones with a S2O2 Coordination Mode and Their Insulin-Mimetic Activities”, Heterocycles, 2007, 73, 603–615.

  25. (25)M. Yamaguchi, R. Saito, K. Utsumi, A. Ochiai, N. Kawashima, Y. Tokuoka, and A. Katoh, “The Nicotinic Acid-p-Aminophenylalanine-Hydroxybenzoic Acid Triads Induce apoptosis in Human Leukemia U937 Cells”, Heterocycles, 2007, 71(7), 1503–1508.

  26. (26)Akira Katoh, Kayo Kameo, Ryota Saito, and Yuriko Matsumura, “Synthesis of New 2,4-Pteridinediones and Their Application to Fluorescence Derivatization Reagents”, J. Fac. Sci. Tech., Seikei Univ., 2007, 44(2), 53–64

  27. (27)R. Saito, A. Katoh, and Y. Inoue, “Unusual Temperature Dependence of Enantioselectivity in Asymmetric Reductions by Chiral NADH Models”, Org. Lett., 2006, 8 (10), 2067–2070.

  28. (28)A. Katoh, M. Yamaguchi, K. Taguchi, R. Saito, Y. Adachi, Y. Yoshikawa, and H. Sakurai, “Oxovanadium(IV) and (V) Complexes with 3-Hydroxy-4(1H)-pyridinones and 1-Hydroxy-2(1H)-pyrimidinones – Synthesis, Structural Characteristics, and Their Insulin-mimetic Activities”, Biomedical Research on Trace Elements, 2006, 1–10.

  29. (29)M. Yamaguchi, K. Wakasugi, R. Saito, Y. Adachi, Y. Yoshikawa, H. Sakurai, and A. Katoh, “Syntheses of vanadyl and zinc(II) complexes of 1-hydroxy-4,5,6-substituted 2(1H)-pyrimidinones and their insulin–mimetic activities”, J. Inorg. Biochem, 2006, 100, 260–269.

  30. (30)A. Katoh, K. Harada, and R. Saito, “Synthesis and Characterization of Fe(III) and Pb(II) Complexes with 3-Hydroxypyridine-2(1H)-thiones”, Hemoglobin, 2006, 30(1), 81–92.

  31. (31)A. Katoh, K. Ogino, and R. Saito, “Synthesis of New 3-Hydroxy-4(1H)-pyridinone Directly Attached to Quinoxaline and Its Fluorescence Property upon Complexation to Metal Ions”, Heterocycles, 2005,  65(9), 2195–2201.

  32. (32)A. Katoh, A., R. Yamamoto, T. Fujimoto, R. Saito, “High-performance Liquid Chromatographic Enantioseparation Based on Diastereomer Formation With New Fluorescent Chiral Quinoxalines.” Heterocycles 2005, 65(5), 1111–1120.

  33. (33)A. Katoh, H. Kudo, R. Saito, “Allosteric binding of alkali metal ions to a pseudocryptand formed by a C-pivot tripodal ligand containing 3-hydroxy-2(1H)-pyridinone and Ga(III)” Heterocycles, 2005, 66, 285–297.

  34. (34)A. Katoh, M. Yamaguchi, R. Saito, Y. Adachi, and H. Sakurai, “Insulinomimetic Vanadyl-Hydroxythiazolethione Complexes with VO(S2O2) Coordination Mode: The Correlation between the Activity and Hammett's Substituent Constant”, Chem. Lett., 2004, 33, 1274–1275.

  35. (35)R. Saito, N. Suga, A. Katoh, S. Maki, T. Hirano, and H. Niwa, “6,8-Diarylimidazo[1,2-a]pyrazin-3(7H)-ones as Potential Chemiluminescent pH/Superoxide Double Sensors”, Luminescence, 2004, 19, 172.

  36. (36)R. Saito, E. Iwasa, and A. Katoh, “Studies on the Chemiluminescence Mechanism of Cypridina Luciferin Analogues: Dissociation Constants of Singlet-Excited Cypridina Oxyluciferin Analogues”, Luminescence, 2004, 19, 148.

  37. (37)Y. Nishiyama, M. Kaneda, R. Saito, T. Mori, T. Wada, and Y. Inoue, “Enantiodifferentiating Photoaddition of Alcohols to 1,1-Diphenylpropene in Supercritical Carbon Dioxide: Sudden Jump of Optical Yield at the Critical Density”, J. Am. Chem. Soc., 2004, 126 (21), 6568–6569.

  38. (38)R. Saito, C. Inoue, and A. Katoh, “Well-divided and pH-Dependent Bimodal Chemiluminescence of 2-Methyl-6-phenyl-8-(4-substituted phenyl)imidazo[1,2-a]pyrazin-3(7H)-ones Induced by Superoxide Anion”, Heterocycles, 2004, 63(4), 759–764.

  39. (39)S. Horiya, X. Li, G. Kawai, R. Saito, A. Katoh, K. Kobayashi, and K. Harada, “RNA LEGO: Magnesium-Dependent Formation of Specific RNA Assemblies through Kissing Interactions”, Chemistry & Biology, 2003, 10, 645–654.

  40. (40)A. Katoh, K. Taguchi, R. Saito, Y. Fujisawa, T. Takino, and H. Sakurai, “Oxovanadium Complexes of N-Substituted 2-Hydroxy-2-methyl-4(1H)-pyridinones: Synthesis, Spectroscopic Characterization, and the Insulin-Mimetic Activity”, Heterocycles, 2003, 60(5), 1147–1159.

  41. (41)A. Katoh, H. Kudo, and R. Saito, “Allosteric Binding of Alkali Metal Ions to a Pseudocryptand Formed by a Tripodal Heterocyclic Hexadentate Ligand and Ga(III)”, J. Supramol. Chem., 2003, 2, 79–84.

  42. (42)A. Katoh, Y. Inoue, H. Nagashima, Y. Hikita, J. Ohkanda, and R. Saito, “Synthesis of Linear and Cyclic Hexapeptides with N-(1,2-Dihydro-1-hydroxy-2-oxopyrimidin-4-yl)-L-Lysyl-beta-alanyl as the Repeating Unit and Properties of Their Iron(III) Complexes”, Heterocycles, 2002, 58, 371–381.

  43. (43)R. Saito, K. K. Ghosh, K. Harada, A. Katoh, “Microbial Growth-Promotion Activity of 3-Hydroxymonoazine- and N-Hydroxydiazine-Type Heterocycles”, Yakugaku Zasshi, 2002, 122, 703–705.

  44. (44)R. Saito, M. Kaneda, T. Wada, A. Katoh, and Y. Inoue, “First Asymmetric Photosensitization in Supercritical Fluid.  Exceptionally High Pressure/Density Dependence of Optical Yield in Photosensitized Enantiodifferentiating Isomerization of Cyclooctene”, Chem. Lett., 2002, 31, 860–861.

  45. (45)A. Katoh, T. Tsukahara, R. Saito, K. K. Ghosh, Y. Yoshikawa, Y. Kojima, A. Tamura, and H. Sakurai, “An Extremely High Insulin-Mimetic Activity of Bis(1,4-Dihydro-2-methyl-1-phenyl-4-thioxo-3-pyridinolato)zinc(II) Complex”, Chem. Lett., 2002, 31, 114–115.

  46. (46)A. Katoh, T. Tsukahara, R. Saito, Y. Yoshikawa, Y. Kojima, and H. Sakurai, “Synthesis of Vanadyl and Zinc(II) Complexes of N-Substituted 3-Hydroxy-4(1H)-pyridinethiones and Their Insulin-Mimetic Activities”, J. Inorg. Biochem., 2001, 86(1), 293.

  47. (47)A. Katoh, Y. Hikita, M. Harata, J. Ohkanda, T. Tsubomura, A. Higuchi, R. Saito, and K. Harada, “3-Hydroxy-4(1H)-pyridone-Containing Linear and Cyclic Hexapeptides and Their Iron(III) Complexes, Synthesis, Property, and the Growth-Promotion Activity”, Heterocycles, 2001, 55 (11), 2171–2187.

  48. (48)R. Saito, T. Hirano, H. Niwa, and M. Ohashi, “Substituent Effects on the Chemiluminescence Properties of Coelenterazine Analogues”, Chem. Lett., 1998, 27, 95–96.

  49. (49)R. Saito, T. Hirano, H. Niwa, and M. Ohashi, “Solvent- and Substituent Effect on the Fluorescent Properties of Coelenteramide Analogues”, J. Chem. Soc., Perkin Trans. 2, 1997, 1711–1716.

Publication List